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Considering that its 1st advertising and marketing in 1985, Misoprostol has been approved in greater than 85 countries. Misoprostol is utilized: To avoid development of stomach ulcers, which could possibly quite often be triggered by arthritis medicines that happen to be referred to as non-steroidal anti-inflammatory drugs (NSAIDs) To treat acute ulcers within the stomach (gastric ulcers), or in the 1st part of the smaller intestine (duodenal ulcers) To stop bleeding within the stomach or upper intestine in hospital patients right after surgery Misoprostol protects the stomach lining from ulcerating effects of NSAIDs (for example aspirin and ibuprofen) and prevents stomach ulceration and associated ulcer complications (like ulcer bleeding, obstruction, and perforation). Misoprostol is really equivalent to a group of substances known as prostaglandins, which take place naturally within the stomach and also other parts with the physique. 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