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Nexium is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, promote healing of erosive esophagitis, eradication of Helicobacter pylori together with antibiotics, preventive therapy of ulcers after treatment with anti-inflammatory non-steroid medications. Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Nexium increases blood levels of diazepam (Valium) by decreasing the elimination of diazepam in the liver. Nexium and other PPIs reduce the absorption and concentration in blood of ketoconazole (Nizoral) and increase the absorption and concentration in blood of digoxin (Lanoxin). Co-administration of Nexium with Clarithromycin increaes area under the plasma concentration time curve (AUC) of the first. Nexium may slow down metabolism of such medications: citalopram, diazepam, clomipramine, phenytoin, imipramine. Consequently their dose should be corrected. 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If your condition requires treatment with Nexium and antibiotics follow all instructions of your doctor to achieve the best results. Do not stop taking this medication even if your symptoms improved as your illness may not be completely treated. If you are pregnant, plan to become pregnant or breastfeeding consult your physician about it before to take this medication. If you missed a dose take it the soonest. If it is almost time of your next dose just skip it and return to your regular dosage schedule. Never double dose this medication to compensate the missed dose. Storage Disclaimer If overdose of Nexium was taken the following symptoms occur: confusion, headache, drowsiness, blurred vision, rapid heartbeat, nausea, xerostomia (dry mouth), sweating, flushing, shallow breathing or shortness of breath, tremor, coordination dysorders, or seizure. 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