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Before taking Norvasc, inform your doctor if you have congestive heart failure or liver disease. Common use This medication belongs to the group of calcium channel blockers. Norvasc selectively blocks channels of L-type (one of six types of channels in tissues) located in a vascular wall, myocard and in particular in cells of conducting and contractile systems of myocardium. By blocking Ca+ ions transfer through membrane Norvasc decreases tone of vessels, arterial pressure. The medication is used to treat hypertension, ischemic heart disease, angina. Drug interaction Overdose Medications which contain A2+ may decrease Norvasc effect. Non-steroid anti-inflammatory medications and estrogens may decrease effectiveness of Norvasc. Diuretics may increase Norvasc activity. Concomitant taking with medications containing lithium might aggravate their toxicity. 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By blocking Ca+ ions transfer through membrane Norvasc decreases tone of vessels, arterial pressure. The medication is used to treat hypertension, ischemic heart disease, angina. Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment. Medications which contain A2+ may decrease Norvasc effect. Non-steroid anti-inflammatory medications and estrogens may decrease effectiveness of Norvasc. Diuretics may increase Norvasc activity. 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